Eleanor Barnes is an MRC Senior Clinical Fellow and an honorary consultant in hepatology at Oxford University and the John Radcliffe hospital. She has spent recent years working on translational T and B cell immunology. She has a long standing interest in the immune control of hepatitis infection, most recently developing T cell vaccines against HCV, which are now being tested for efficacy in intra-venous drug using populations in collaboration with industry. She is also developing T cell vaccines for HBV immunotherapy. She is leading the UK wide MRC funded consortium STOP-HCV using stratified medicine to optimise patient clinical outcomes integrating viral and host genomics with immune biomakers. Recently her group has been establishing clinical cohorts and investigating the pathogenesis of IgG4 related systemic disease, a B cell disease associated with inflammation, fibrosis and organ failure.