Piet Gros (1962) studied chemistry at the University of Groningen (1985), received his PhD degree cum laude in protein crystallography at the University of Groningen (1990) and performed post-doctoral research at the ETH in Zürich (Switzerland) and at Yale University, New Haven CT (USA). In 1994 he established a research group in protein crystallography at the Utrecht University (The Netherlands), where he obtained a permanent position in 1998 and became full professor in 2002. He heads the laboratory of Crystal and Structural Chemistry, was chair of the Department of Chemistry (2007-2010), scientific director of the Bijvoet Center (2012-2016); and, initiated and leads the bachelor program Molecular Life Sciences in Utrecht.
He was awarded a Pionier (2000) by the Council of Chemical Sciences (NWO, The Netherlands), received an ERC Advanced Grant (2008) by the ERC Council (EU), was recipient of the Spinoza prize (2010) by NWO (The Netherlands), was elected member of the Royal Academy of Arts and Sciences KNAW (2010), became Knight in the Order of the Netherlands Lion (2013), and was elected EMBO member (2013).
With his research group, he studies the mechanisms of molecular recognition and regulation underlying biologically and biomedically important processes. His major expertise is in protein chemistry and crystallography to understand large human proteins and membrane proteins, with a particular focus on the immune system. Key insights have been obtained into outer-membrane proteins of pathogenic bacteria, the adhesive role of Von Willebrand factor in platelet aggregation and wound healing. Moreover, the group is world leading in the structural biology of the complement cascade of the mammalian (human) immune system.